Reading the third issue of the Ultimates…
Cap accidentally breaks Nick Fury’s nose, and apologizes.
Fury responds “Take it easy, Cap, this nose has been smashed more often than Robert Downey Junior.”
This issue came out six years before the Iron Man movie, so technically, this is Nick Fury - who looks like Sam Jackson six years before it was relevant - making a pop culture joke about RDJ being a drunk - six years before it was relevant.
Please excuse me while my head explodes.
